Figure 6

Schematic model of shrimp immune system in early life stages of P. monodon, including nauplius, zoea, mysis and 15-day-old postlarva. Pattern recognition proteins (PRPs) (beta 1,3-glucan binding protein (BGBP), lipopolysaccharide and beta 1,3-glucan binding protein (LGBP) and lectin), prophenoloxidase system (proPO system) (prophenoloxidase-activating factor 1 (PPAF1), prophenoloxidase-activating factor 2 (PPAF2) and serpin), antimicrobial peptides (AMPs) (crustin, anti-lipopolysaccharide factor (ALF) and antiviral protein), blood clotting system, Toll pathway (toll receptor, Spätzle and tumor necrosis factor receptor-associated factor 6 (TRAF6)), IMD pathway (Relish) and stress responses (heat shock proteins (HSPs) and manganese superoxide dismutase (MnSOD) were involved in early life stages of shrimp. Blue box represents transcript expression found associated with the four larval stages, while orange box represents an immune gene with increasing expression pattern during the development. The compotents in shrimp immune pathways were adapted from previous studies³¹.