Figure 2 | Scientific Reports

Figure 2

From: Radiation exposure induces cross-species temporal metabolic changes that are mitigated in mice by amifostine

Figure 2

Combined metabolomic analysis following 60Co γ-radiation exposure. (A) Cohort 1 (mice) NMR metabolic trajectories of radiation (top) and Sham (bottom) calculated by PLS from baseline (5H) and visualized across time (Q2). *Indicates model p-values < 0.05. (B) Cohort 1 (mice) MetaboAnalyst pathway enrichment with pathways displayed by fold enrichment. (C) Cohort 2 (NHP) metabolic trajectories show 5.8 Gy radiation (top) and 7.2 Gy radiation (bottom) calculated by PLS from baseline (5H) and visualized across time (Q2). *Indicates model p-values < 0.05 (D) Cohort 2 (NHP) MetaboAnalyst pathway enrichment analysis with pathways displayed by fold enrichment.

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