Table 2 Experimental result using the multiclass model for the number of predicted CMB and iron deposit lesions evaluated against the reference annotation.
Experiments | Avg. sensitivity ± SEM [CI lower, upper] | Avg. precision ± SEM [CI lower, upper] | Avg. magnitude. Accuracy ± SEM [CI lower, upper] | Pearson correlation coeff. (p-value) | Bland–Altman plot (md, [lower, upper]) | |
---|---|---|---|---|---|---|
Multi-class CMB | SWI | 0.82 ± 0.07 CI [0.68, 0.96] | 0.36 ± 0.06 CI [0.24, 0.49] | 0.99 ± 0.06 CI [0.87, 1.12] | 0.96 (p = 0.000) | md = 0.04 CI [− 26.61, 26.70] |
SWI and QSM | 0.84 ± 0.07 CI [0.70, 0.98] | 0.59 ± 0.08 CI [0.43, 0.75] | 1.15 ± 0.07 CI [1.00, 1.29] | 0.99 (p = 0.000) | md = 0.67 CI [− 18.26, 19.59] | |
SWI and T2w | 0.76 ± 0.08 CI [0.60, 0.91] | 0.43 ± 0.06 CI [0.31, 0.56] | 1.00 ± 0.07 CI [0.86, 1.13] | 0.97 (p = 0.000) | md = 0.75 CI [− 25.47, 26.97] | |
SWI, QSM and T2w | 0.89 ± 0.05 CI [0.79, 1.00] | 0.49 ± 0.06 CI [0.37, 0.61] | 1.07 ± 0.06 CI [0.95, 1.19] | 0.98 (p = 0.000) | md = 0.92 CI [− 25.49, 27.33] | |
Multi-class iron deposits | SWI | 0.76 ± 0.06 CI [0.63, 0.88] | 0.70 ± 0.08 CI [0.55, 0.86] | 1.13 ± 0.07 CI [0.99, 1.28] | 0.91 (p = 0.000) | md = 13.83 CI [− 62.08, 89.75] |
SWI and QSM | 0.75 ± 0.07 CI [0.62, 0.88] | 0.75 ± 0.08 CI [0.60, 0.91] | 1.20 ± 0.05 CI [1.11, 1.30] | 0.91 (p = 0.000) | md = 6.71 CI [− 74.77, 88.18] | |
SWI and T2w | 0.76 ± 0.06 CI [0.64, 0.89] | 0.60 ± 0.08 CI [0.44, 0.75] | 1.08 ± 0.07 CI [0.93, 1.22] | 0.87 (p = 0.000) | md = 18.29 CI [− 71.54, 108.12] | |
SWI, QSM and T2w | 0.81 ± 0.05 CI [0.71, 0.92] | 0.64 ± 0.08 CI [0.49, 0.79] | 1.17 ± 0.05 CI [1.08, 1.27] | 0.90 (p = 0.000) | md = 16.29 CI [− 62.23, 94.82] |