Table 1 Total bone marrow cellularity and frequencies of cell populations within the bone marrow.

From: Acute fat loss does not affect bone mass

Cell population

tg veh

tg dim

P-value

Total cellularity (× 106 cells)

12.7 ± 3.3

13.6 ± 2.2

0.512

Lymphocytes (% of alive)

41.0 ± 5.7

45.8 ± 5.0

0.107

T cells (% of lymphocytes)

10.6 ± 1.7

7.9 ± 1.0

0.002

CD4+ T cells (% of lymphocytes)

1.4 ± 0.5

1.0 ± 0.2

0.018

CD8+ T cells (% of lymphocytes)

2.5 ± 0.6

1.8 ± 0.5

0.031

CD4-CD8- T cells (% of lymphocytes)

6.6 ± 1.1

5.1 ± 0.7

0.006

B cells (% of lymphocytes)

30.5 ± 8.1

41.0 ± 6.0

0.013

Pro/pre B cells (% of lymphocytes)

20.8 ± 3.6

33.7 ± 4.8

 < 0.001

Immature B cells (% of lymphocytes)

2.5 ± 0.8

3.3 ± 0.6

0.058

Recirculating B cells (% of lymphocytes)

7.6 ± 3.0

7.3 ± 4.2

0.876

Hematopoietic cells (% of alive)

80.4 ± 10.1

85.8 ± 5.0

0.153

Hematopoietic stem cells (% of alive)

0.33 ± 0.10

0.34 ± 0.06

0.752

Neutrophils (% of alive)

21.6 ± 9.8

22.3 ± 8.0

0.872

Monocytes (% of alive)

1.7 ± 0.4

1.6 ± 0.5

0.662

Macrophages (% of alive)

1.0 ± 0.2

1.1 ± 0.4

0.835

Pre-osteoclasts (% of alive)

0.16 ± 0.07

0.15 ± 0.05

0.834

  1. Data are arithmetic mean ± standard deviation. tg, transgene; veh, vehicle; dim, dimerizer n = 10 veh and 10 dim mice. Student’s t-test.
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