Figure 4
From: New candidate blood biomarkers potentially associated with white matter hyperintensities progression
Biomarker concentrations in the replication phase (n = 160). Lines represent adjusted means from baseline to the follow-up visit in cases (black) and controls (grey). Error bars represent the standard error of the adjusted mean. These adjusted means have been extracted from mixed models and were corrected for baseline age, sex, visit, change in systolic blood pressure, and baseline WMH. *: p-value < 0.05 between groups at the baseline visit or at the follow-up visit. #: group and visit interaction p-value < 0.05. This interaction term represents the difference in the rate of changes between groups in biomarker concentrations.
