Table 3 Comparison of clinical data between the CNV status among the subjects, n (%) or medians (IQRs).

From: Copy number variation in the CES1 gene and the risk of non-alcoholic fatty liver in a Chinese Han population

Variables

Case (n = 303)

Control (n = 303)

P-value*

Losses

(n = 25)

Neutral

(n = 194)

Gains

(n = 84)

P-value*

Losses

(n = 12)

Neutral

(n = 215)

Gains

(n = 76)

ALT (IU/L)

28.00 (17.50, 42.50)

27.00 (21.00, 38.25)

31.00 (23.00, 42.75)

0.17

20.50 (16.25, 33.75)

19.00 (14.00, 26.00)

18.50 (15.00, 26.75)

0.38

AST (IU/L)

23.00 (18.00, 31.50)

22.00 (19.00, 28.00)

24.00 (20.00, 31.00)

0.12

24.50 (20.00, 30.75)

20.00 (17.00, 24.00)

21.00 (18.00, 27.00)

0.06

GGT (IU/L)

27.00 (21.00, 37.00)

30.00 (22.00, 46.00)

34.00 (24.00, 47.75)

0.27

21.50 (13.25, 28.75)

22.00 (16.00, 32.00)

24 (17.00, 33.50)

0.70

TC (mmol/L)

4.96 (4.30, 5.63)

5.09 (4.50, 5.88)

5.17 (4.60, 5.73)

0.72

4.68 (4.21, 5.12)

4.94 (4.49, 5.43)

4.92 (4.37, 5.44)

0.37

TG (mmol/L)

1.48 (1.29, 2.10)

1.82 (1.29, 2.69)

1.76 (1.20, 2.48)

0.35

1.15 (0.81, 1.51)

1.12 (0.88, 1.48)

1.12 (0.86, 1.44)

0.92

HDL-C (mmol/L)

1.17 (0.97, 1.30)

1.21 (1.04, 1.37)

1.19 (0.98, 1.39)

0.58

1.33 (1.11, 1.51)

1.35 (1.20, 1.48)

1.37 (1.20, 1.48)

0.74

LDL-C (mmol/L)

3.09 (2.52, 3.75)

3.12 (2.54, 3.80)

3.14 (2.63, 3.65)

0.83

2.75 (2.40, 3.32)

3.03 (2.61, 3.49)

2.99 (2.65, 3.57)

0.40

CES1 (ng/ml)

17.95 (11.91, 27.97)

13.25 (10.61, 18.65)

13.25 (10.42, 17.68)

0.07

12.88 (8.28, 17.03)

13.13 (10.50, 21.41)

13.13 (10.73, 20.99)

0.54

  1. CNVs, copy number variation; IQR, interquartile range; ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, gamma-glutamyltransferase; TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; CES1, carboxylesterase 1.
  2. *P-values were calculated by using the Chi-square test for categorical variables and Kruskal Wallis test for continues variables.