Table 1 Clinical features of enrolled patients.
ID | Age at HSCT, years | Time from diagnosis to HSCT, years | Time from last hospitalization, days | Gender | Diagnosis | Complete remission at transplant | Conditioning regimen (ATG) | Source of HSC | Type of Transplant | VOD | Day of VOD diagnosis | VOD grade | BSI (day) | GvHD grade (day) | EN |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
#1 | 16.6 | 0.3 | 108 | M | MDS | No | BUS + EDX + L-PAM (ATG) | PBSC | MUD | Yes | 10 | 3 | No | I (+ 20) | No |
#2 | 8.5 | 0.8 | 51 | F | ALL | 1st CR | BUS + THIO + EDX (ATG) | BM | MUD | Yes | 19 | 3 | No | Yes | |
#3 | 14.3 | 2.3 | n.e. | F | ALL | 2nd CR | BUS + THIO + EDX (ATG) | BM | MUD | Yes | 18 | 4 | No | Yes | |
#4 | 9.3 | 10.0 | 11 | F | TM | No | BUS + THIO + FLUDA (ATG) | BM | MUD | Yes | 17 | 4 | E. coli (+ 8) | No | |
#5 | 5.5 | 2.5 | 109 | M | ALL | 2nd CR | THIO + TREO + FLUDA | BM | Haploidentical | Yes | 26 | 4 | No | III–IV (+ 22) | No |
#6 | 18.2 | 0.5 | 19 | M | AML | 1st CR | BUS + EDX + L-PAM (ATG) | PBSC | MUD | Yes | 21 | 3 | No | Yes | |
#7 | 3.0 | 0.8 | 69 | F | MDS | No | BUS + EDX + L-PAM (ATG) | BM | MUD | Yes | 15 | 4 | No | Yes | |
#8 | 1.0 | 0.4 | 5 | F | ALL | 1st CR | BUS + THIO + EDX | BM | MFD | Yes | 15 | 4 | No | II (+ 35) | No |
#9 | 1.3 | 0.4 | 13 | M | AML | 1st CR | BUS + EDX + L-PAM | BM | MFD | Yes | 25 | 3 | No | No | |
#10 | 4.6 | 0.8 | 32 | F | ALL | 2nd CR | BUS + THIO + EDX (ATG) | BM | MUD | No | No | Yes | |||
#11 | 20.6 | 0.8 | 93 | M | ALL | 1st CR | BUS + THIO + EDX (ATG) | BM | MUD | No | No | II (+ 15) | No | ||
#12 | 8.1 | 5.2 | 15 | M | ALL | 3rd CR | BUS + THIO + FLUDA | BM | Haploidentical | No | No | Yes | |||
#13 | 10.5 | 3.8 | 133 | F | AML | 2nd CR | THIO + TREO + FLUDA | BM | MFD | No | S. epidermidis, E. faecalis (+ 6) | No | |||
#14 | 15.9 | 1.2 | 18 | F | AML | 2nd CR | BUS + THIO + FLUDA | BM | Haploidentical | No | No | II (+ 36) | Yes | ||
#15 | 0.9 | 0.6 | 69 | F | ALL | 1st CR | BUS + THIO + EDX (ATG) | BM | MUD | No | E. coli (+ 2) | No | |||
#16 | 6.0 | 4.4 | 12 | M | TM | No | BUS + THIO + FLUDA (ATG) | BM | MUD | No | No | II (+ 26) | No | ||
#17 | 14.4 | 0.3 | 48 | F | AML | 2nd CR | BUS + EDX + L-PAM (ATG) | BM | MUD | No | E. coli, E. faecium, S. warneri (+ 5) | I (+ 23) | Yes | ||
#18 | 2.2 | 0.4 | 150 | F | JMML | No | BUS + EDX + L-PAM (ATG) | BM | MUD | No | S. epidermidis, S. vestibularis (+ 36) | I (+ 35) | Yes |
