Figure 2 | Scientific Reports

Figure 2

From: Cytotoxic effects and tolerability of gemcitabine and axitinib in a xenograft model for c-myc amplified medulloblastoma

Figure 2

Cytotoxic effect of various cytostatic drugs and inhibitors in vitro. (a) MB3W1 cells were treated in vitro with various cytostatic drugs and inhibitors for 48 h before staining with annexin V/Live-Death-staining and flow cytometry analyses. Graph shows the respective EC50 –values (Mean ± SD; combined data from five independent experiments; **, p = .0079) (b) EC50 –values for a panel of inhibitors of the VEGFR. (c) Relative cell viability after cisplatin/etoposide phosphate, gemcitabine, axitinib and gemcitabine/axitinib treatment and corresponding EC50 (dotted line).

Back to article page