Figure 3

The gene expression profiles in miR-378a overexpressed NHEK cells. (a) Heatmap of DEGs in keratinocytes over-expressing miR-378a for 24 h (1233 genes; left) and 48 h (112 genes with |log(fold-change)| > 1.5; right). The heatmaps were drawn using ComplexHeatmap R package. (b) The top overlapped KEGG pathways associated with up- and down-regulated genes at both 24 h and 48 h post-transfection of miR-378a mimic. The figures were drawn using tidyverse R package.