Figure 5

Identification of candidate gene targets of miR-378a. (a) Venn diagram shows the overlaps of genes down-regulated (DM) in cells transfected with miR-378a mimic for 24 h and 48 h and genes up-regulated (UI) in cells transfected with miR-378a inhibitor for 24 h and 48 h. (b) Venn diagram shows the overlaps of genes identified in (a) and target genes of miR-378a predicted by three different databases (see “Materials and methods” section).