Figure 2
From: Smoking accelerates renal cystic disease and worsens cardiac phenotype in Pkd1-deficient mice
(a) Analysis of the effects of smoking and Pkd1 deficiency in SUN on NC (n = 6), NCS (n = 4), CY (n = 10) and CYS (n = 11) mice. (b) Analysis of the effects of smoking and the Pkd1flox/-:Nestincre genotype in the global renal cystic index on CY-Pkd1flox/flox:Nestincre (n = 8), CYS-Pkd1flox/flox:Nestincre (n = 6), CY-Pkd1flox/-:Nestincre (n = 3) and CYS-Pkd1flox/-:Nestincre (n = 5) mice. These analyses were performed using aligned rank transform followed by two-way analysis of variance. (c) Representative images of the renal cystic phenotype in the absence and presence of smoking.
