Table 2 Experimental setup investigating the effect of Comp23 in DSS-induced colitis of WT mice.

From: Immunomodulatory role of Parkinson’s disease 7 in inflammatory bowel disease

  1. During the experiment, WT mice received water for 10 days (Control and Comp23 groups) or 2.5% DSS in their drinking water for 7 days, then clear water for 3 days (DSS and DSS + Comp23 groups). Mice were treated with daily by intraperitoneal injection of Comp23 (Comp23 and DSS + Comp23 groups) or vehicle only (Control and DSS groups). Changes in the body weight of mice and disease activity index (DAI) were monitored during the whole experiment. Experiments were termined on the 7th or 10th day. Spleen weights were measured from samples derived from 7 and 10th days. Molecular biological measurements were performed on tissue samples derived from 7th day.