Figure 6

Nanofiber immunizations persist at injection sites independent of antigen loading density. (A) Representative FMT images of mice injected with fluorescently labeled gp120 or gp120 nanofibers at 0- and 1- and 6-h post injection. (B) Fluorescence signal at injection site for gp120^high-Q11 and gp120^low-Q11 immunizations for up to 72 h post injection. (n = 3 mice/group, compared using a repeated measures non-parametric test, no significant difference between groups). (C) Remaining fluorescent signal in skin sections at sacrifice, 6 days post-immunization. (n = 3 mice/group, compared by Kruskal–Wallis, p = 0.065).