Scientific Reports

Table 5 List of the 3D structures of the key DDR proteins available from the PDB database.

From: A computational and structural analysis of germline and somatic variants affecting the DDR mechanism, and their impact on human diseases

	Region	Method	PDB id	Resolution	Chains
ATM	1–3056	Cryo-EM	5np0	5.70 Å	A/B
	1–3056	Cryo-EM	5np1	5.70 Å	A
	3024–3030	NMR	6hka	–	A
BRCA1	1–110	NMR	1jm7	–	A
	1646–1859	X-ray	1jnx	2.50 Å	X
	1646–1859	X-ray	1n5o	2.80 Å	X
	1755–1863	NMR	1oqa	–	A
	1646–1859	X-ray	1t15	1.85 Å	A
	1646–1859	X-ray	1t29	2.30 Å	A
BRCA2	1517–1551	X-ray	1n0w	1.70 Å	B
BRCA2	21–39	X-ray	3eu7	2.20 Å	A
MUTYH	76–362	X-ray	3n5n	2.30 Å	X/Y
MUTYH	356–497	NMR	1x51	–	A

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