Figure 2

Family pedigree and the filtering process for WES data. (A) Family pedigree consists of one proband. I-1 represents the proband’s father; I-2 represents the proband’s mother; II-1 represents the proband. (B) The filtering process for WES data, containing 81,567 total coding variants. Filtering results: 1315 deleterious variations, two variants selected from genetic analysis, final gene associated with this phenotype variation.