Figure 3

The ELN mutation site and its conservation. (A) Human ELN gene maps to chromosome 7q11.23 and contains 34 exomes. The base pair mutation site is c.1939G>T, which is located on the exome 27 of ELN. (B) The proband and her father were confirmed to be heterozygous carriers of 1939G>T hybridization, and her mother was homozygous negative for this mutation, as shown by Sanger sequencing.