Figure 1
From: Quantification of early learning and movement sub-structure predictive of motor performance

Mouse undergoing a video-rotarod trial. (A) Mouse complying with the movement of a rotating rod. A gray colored rectangle outlines the region of interest around the paw (or foot) that the program utilizes to locate serial paw positions. (B) Horizontal paw position, speed and acceleration of the right hind limb paw of a mouse over the course of its first rotarod trial. (C) Vertical paw position, speed and acceleration of the right hind limb paw of a mouse over the course of its first rotarod trial. Grey and black lines bracket the data analyzed in similarly colored graphs in (D). (D) Example normalized spectrograms illustrating the computation of spectral arc length to measure movement smoothness. Paw speed earlier in the trial (grey), which undergoes more regular speed deflections, is associated with a normalized spectrogram (grey) with less prominent peaks and thus with a smaller absolute spectral arc length. A less negative, closer to zero, magnitude of this value indicates greater smoothness.