Figure 9
From: Quantification of early learning and movement sub-structure predictive of motor performance
Impact of baclofen on first trial features. (A–C) Rotarod score and mouse weight (A) and vertical height and horizontal (B,C) intra-session first trial features in control (n = 9) and baclofen-injected mice (n = 10). Bar charts illustrate means; error bars represent S.E.M for rotarod score and intra-session features for right hind-limb paw position. Significant changes in some intra-session features are notable despite lack of change in rotarod scores. (D) Scores derived from principal component analysis (PCA) reveals distinct distributions (p < 0.0001, MANOVA-Wilks test) for baclofen-injected (n = 10) and control mice (n = 9). Each dot represents one mouse. Values along an axis represent PCA scores for that principal component. A mouse can be represented in multi-dimensional space with each intra-session feature comprising one dimension. Dimensionality reduction with PCA reveals separate groups. * = p < 0.05; ** = p < 0.01; **** = p < 0.0001, (unpaired Student’s t-test).
