Figure 4 | Scientific Reports

Figure 4

From: Multi-omics integration of methyltransferase-like protein family reveals clinical outcomes and functional signatures in human cancer

Figure 4

Proteogenomic landscape and functional dependency of METTLs in cancer cell lines. (A) Relative protein abundance of METTL1 in more than 300 CCLE lines across 22 lineages. (B) Bar graph showing mean of each METTL dependency score in genome-scale loss-of-function screens of 808 tumor lines. (C) Distribution of METTL1 dependency CERES score and its correlation with its cofactor WDR4 in 789 CCLE lines.

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