Figure 6 | Scientific Reports

Figure 6

From: Exome sequencing identifies novel somatic variants in African American esophageal squamous cell carcinoma

Figure 6

Summary of significantly altered genes in AA ESCC. (a) Genes that were mutated, or amplified in proliferation, cell cycle and cell cycle checkpoint controls. (b) Amplified genes found in squamous cell homeostasis, epithelial to mesenchymal transition (EMT), invasion and metastasis. (c) Genes that were amplified or mutated in receptor tyrosine kinase (RTK) and signaling pathways (d) Chromatin remodeling genes that were amplified, deleted, or mutated. Red designates amplification, blue indicates deletion, and purple shows missense mutations. Figure was created with BioRender.com.

Back to article page