Table 1 Clinicopathological features of a total 30 LSCC patients.

From: MCM-2, Ki-67, and EGFR downregulated expression levels in advanced stage laryngeal squamous cell carcinoma

Clinicopathological features

Total

MCM-2

p-value

Ki-67

p-value

EGFR

p-value

Total

30 (100%)

162.4333

 

32.9567

 

165.0090

 

Histological differentiation

  

0.351

 

0.148

 

0.729

Well

17 (56.67%)

169.4471

 

40.4824

 

162.2394

 

Moderate

13 (43.33%)

153.2615

 

23.1154

 

168.6308

 

Lymphatic metastasis

  

0.478

 

0.499

 

0.135

LN negative

24 (80.00%)

161.6583

 

34.6375

 

173.9333

 

Unilateral

3 (10.00%)

142.3333

 

40.3000

 

129.2233

 

Bilateral

3 (10.00%)

188.7333

 

12.1667

 

129.4000

 

Metastasis

  

0.614

 

0.574

 

0.579

No metastasis

25 (83.33%)

164.3840

 

31.4360

 

167.2748

 

Metastasis

5 (16.67)

152.6800

 

40.5600

 

153.6800

 

Stage

  

0.010*

 

0.078

 

0.001*

I

9 (30.00%)

198.2111

 

51.4778

 

184.3889

 

II

1 (3.33%)

216.2000

 

73.5000

 

245.9000

 

III

4 (13.33%)

150.0750

 

21.6000

 

212.3500

 

IV

16 (53.33%)

142.0375

 

22.8437

 

137.2169

 

Recurrent

  

0.416

 

0.523

 

0.128

No

15 (50.00%)

155.4200

 

29.0933

 

178.6713

 

Yes

15 (50.00%)

169.4467

 

36.8200

 

151.3467

 

Survival

  

0.495

 

0.538

 

0.087

> 5 years

17 (56.67%)

167.5824

 

36.2118

 

178.3747

 

< 5 years

13 (43.33%)

155.7000

 

28.7000

 

147.5308

 

Alive

16 (53.33%)

170.9000

0.219

36.6938

0.509

178.6294

0.103

Death

14 (46.67%)

152.7571

 

28.6857

 

149.4429

 
  1. *Differences were statistically significance.