Table 1 Summary of 16S rRNA gene sequencing data and α-diversity values [Shannon index and Faith’s phylogenetic diversity (PD)].

From: W27 IgA suppresses growth of Escherichia in an in vitro model of the human intestinal microbiota

 

Feces

KUHIMM

Control

+ W27 IgA

+ Mouse IgA

Read counts

22,340 ± 3,797

26,063 ± 9,806

27,090 ± 5,774

25,593 ± 6,594

Observed OTUs

380.2 ± 113.7

215.2 ± 74.7*

210.0 ± 56.8

213.0 ± 46.0

Shannon index

7.72 ± 0.54

6.28 ± 0.46*

6.32 ± 0.46

6.35 ± 0.45

Faith’s PD

17.5 ± 5.2

10.6 ± 2.8*

11.7 ± 3.0

10.7 ± 1.4

  1. In addition to twelve human fecal samples (Feces), the corresponding cultures without IgA (Control), the corresponding cultures with W27 IgA (+ W27 IgA), and the corresponding cultures with mouse monoclonal IgA (+ Mouse IgA) were sampled after 48 h of fermentation. The values are represented as mean ± standard deviation.
  2. Asterisks (*) represent significant differences (*p < 0.05) (n = 12) between the microbiota in the original feces and in corresponding cultures without IgA using Wilcoxon signed rank test. Significant differences were not detected between KUHIMMs without and with IgA.
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