Table 3 Comparison of demographic variables, frequency of associated symptoms and main phenotypic variables of the headache between inpatient and outpatient cases.
From: Frequency and phenotype of headache in covid-19: a study of 2194 patients
Variable | Entire study sample (n = 458) | Inpatient cases (n = 107) | Outpatient cases (n = 351) | FDR Adjusted P value |
|---|---|---|---|---|
Median age (years) | 51 (42–61) | 56 (IQR 48–65) | 50 (IQR 40–60) | 0.002 |
Female sex | 330/458 (72.1%) | 69/107 (64.5%) | 261/351 (74.4%) | 0.100 |
Prior history of headache | 223/449 (49.7%) | 60/107 (56.1%) | 163/342 (47.7%) | 0.195 |
Headache as the first symptom | 128/446 (28.7%) | 32/107 (29.9%) | 96/339 (28.3%) | 0.911 |
Duration of headache (days) | 7 (IQR 4–14) | 7 (IQR 4–10) | 7 (IQR 4–15) | 0.098 |
Anosmia | 269/448 (60%) | 69/107 (64.5%) | 200/341 (58.7%) | 0.366 |
Asthenia | 337/458 (73.6%) | 55/107 (51.4%) | 282/351 (80.3%) | 0.001 |
Cough | 294/446 (65.9%) | 87/107 (81.3%) | 207/339 (61.1%) | < 0.001 |
Diarrhea | 185/447 (41.4%) | 51/107 (47.7%) | 134/340 (39.4%) | 0.197 |
Dyspnea | 179/444 (40.3%) | 52/107 (48.6%) | 127/337 (37.7%) | 0.094 |
Fever | 263/444 (59.2%) | 47/107 (43.9%) | 216/337 (64.1%) | < 0.001 |
Myalgia | 228/443 (51.5%) | 50/107 (46.7%) | 178/336 (53.0%) | 0.333 |
Weakness | 238/446 (53.4%) | 27/107 (25.2%) | 211/339 (62.2%) | < 0.001 |
Presence of pneumonia | 152/450 (33.8%) | 102/107 (95.3%) | 50/343 (14.6%) | < 0.001 |
Need for oxygen | 86/447 (19.2%) | 55/107 (51.4%) | 31/340 (9.1%) | < 0.001 |
Headache as the most bothersome symptom | 68/428 (15.9%) | 21/100 (21.0%) | 47/328 (14.3%) | 0.172 |
Median intensity (0–10 NRS) | 7 (IQR 6–8) | 7 (IQR 6–8) | 7 (IQR 6–8) | 0.083 |
Median impairment (0–100% NRS) | 50% (IQR 20–80%) | 60 (IQR 40–80) | 50 (IQR 20–80) | 0.151 |
Frontal topography | 307/433 (70.9%) | 84/107 (78.5%) | 223/326 (68.4%) | 0.093 |
Temporal topography | 190/433 (43.9%) | 34/107 (31.8%) | 156/326 (47.9%) | 0.011 |
Pressing quality | 324/434 (74.7%) | 80/107 (74.8%) | 244/327 (74.6%) | > 0.999 |
Photophobia | 152/456 (33.3%) | 48/105 (45.7%) | 104/351 (29.6%) | 0.009 |
Phonophobia | 147/456 (32.2%) | 41/105 (39.0%) | 106/351 (30.2%) | 0.147 |
Avoidance of physical activity | 289/432 (66.9%) | 62/107 (57.9%) | 227/325 (69.8%) | 0.065 |
Worsening with physical activity | 135/433 (31.2%) | 33/107 (30.8%) | 102/326 (31.3%) | > 0.999 |
Need for acute medication | 413/437 (94.5%) | 101/107 (94.4%) | 312/330 (94.5%) | > 0.999 |
