Figure 1 | Scientific Reports

Figure 1

From: Blunted natriuretic response to saline loading in sheep with hypertensive kidney disease following radiofrequency catheter-based renal denervation

Figure 1

Arterial pressure and heart rate in response to isotonic saline loading. MAP; mean arterial pressure, SBP; systolic blood pressure, DBP; diastolic blood pressure. Data are at baseline; − 60–0 min, during 180 min of saline infusion and during 180 min of recovery post saline infusion. Responses were examined in normotensive and hypertensive CKD sheep at 2 and 11 months after sham (intact) or renal denervation (RDN) procedure. Data are mean ± SE. *P < 0.05, ***P < 0.001, ***P < 0.001 comparing control-intact with CKD-intact, #P < 0.05, ##P < 0.01, ###P < 0.001 comparing CKD-intact with CKD-RDN, †P < 0.05 comparing control-intact with control-RDN from post-hoc analysis following repeated measures ANOVA.

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