Figure 3 | Scientific Reports

Figure 3

From: Blunted natriuretic response to saline loading in sheep with hypertensive kidney disease following radiofrequency catheter-based renal denervation

Figure 3

Urine flow, urinary sodium excretion, cumulative urine and sodium output in response to isotonic saline loading. Responses examined in normotensive sheep and sheep with hypertensive chronic kidney disease (CKD) at 2 and 11 months after sham (intact) or renal denervation (RDN) procedure. Data are at baseline; − 60–0 min, during 180 min of saline infusion and during 180 min of recovery post saline infusion. Data are mean ± SE. *P < 0.05 comparing CKD-intact with control-intact, #P < 0.05, ##P < 0.01, ###P < 0.001 comparing CKD-intact with CKD-RDN, †P < 0.05, ††P < 0.01comparing control-intact with control-RDN, from post-hoc analysis following repeated measures ANOVA. UF urine flow, UNaV urinary sodium excretion.

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