Figure 4 | Scientific Reports

Figure 4

From: Peptide VSAK maintains tissue glucose uptake and attenuates pro-inflammatory responses caused by LPS in an experimental model of the systemic inflammatory response syndrome: a PET study

Figure 4

SUV analysis of organ throughout the experiment using 1-min frames. (A) Right kidney. LPS (7.33 ± 3.09); LPS + VSAK groups (2.77 ± 0.64) at minute 60 (*p = 0.04). This difference was maintained during the 90 min of the experiment. VSAK (2.82 ± 1.42); LPS (8.02 ± 4.61) (*p = 0.04); LPS + VSAK (2.3 ± 0.76) (**p = 0.008). (B) Left kidney. (C) Percentage comparison of injected doses (%ID/g) observed in the kidney, liver, and small intestine. Right kidney: (**p = 0.005); (*p = 0.013); (***p = 0.0005). Although a similar behavior was observed in the left kidney, non-significant differences were found. (D) SUV analysis. Right kidney; (*p = 0.0085). (n = 3 in all groups studied). Differences assessed using two-way ANOVA with Tukey’s multiple comparison tests.

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