Figure 2
From: Methylene blue can act as an antidote to pesticide poisoning of bumble bee mitochondria
Hydrogen peroxide production of mitochondria on pyruvate (ETC complex I substrate) in the presence of mitochondria-targeted pesticides and after MB addition (the data are shown as mean ± SD, n = 6). Pesticides, MB and mitochondria were directly added to the cuvette. MB was added to the concentration of 2 μM. The concentration of the pesticides in cuvette see in Table 1. * Statistically significant differences in the hydrogen peroxide production of mitochondria in the absence and presence of pesticide, p < 0.001. ** Statistically significant differences in the hydrogen peroxide production of mitochondria in the presence of pesticide and pesticide + MB, p < 0.01.
