Figure 6
From: Proteomics and metabonomics analyses of Covid-19 complications in patients with pulmonary fibrosis
Positive differentially expressed metabolites were identified and analyzed using proteomics in Covid-19 patients with progressive pulmonary fibrosis. (a) PLS-DA model plot for positive ion mode. (b) Volcano plots of positive compounds. (c) Heatmap of different positive metabolites (“pheatmap” package in R software v3.5.0, https://www.r-project.org/). (d) Bubble plot of the top 20 KEGG enrichment of positive metabolic pathways. C, Nonprogressive pulmonary fibrosis of Covid-19 patients. D, Progressive pulmonary fibrosis of Covid-19 patients. RichFactor is defined as the number of differential metabolites annotated to the pathway divided by all identified metabolites annotated to the pathway.
