Figure 7 | Scientific Reports

Figure 7

From: Proteomics and metabonomics analyses of Covid-19 complications in patients with pulmonary fibrosis

Figure 7

Association analysis of proteomics and metabolomics in Covid-19 patients with progressive pulmonary fibrosis. (a) Cluster heat map of the correlation between proteomics and metabolomics (“pheatmap” package in R software v3.5.0, https://www.r-project.org/). Each row denotes a differentially expressed metabolite, and each column denote a DEP. Blue, negative correlation; Red, positive correlation. (b) Concentric circles of correlation between differential proteins and differential metabolites. If the angle between a differential protein and differential metabolite is an acute angle (less than 90 degrees), the correlation is positive. If the angle between the differential protein and the differential metabolite is an oblique angle (greater than 90 degrees and less than 180 degrees), the correlation is negative. Starting from the center of the circle, the lines are connected to the differential metabolites and differential proteins. The longer the connection length, the stronger the relationship.

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