Table 1 Subject characteristics.

From: Endotrophin and C6Ma3, serological biomarkers of type VI collagen remodelling, reflect endoscopic and clinical disease activity in IBD

 

CD n = 65

UC n = 107

IBS n = 18

HS n = 20

Age

Mean (range)

36.32 [18–76]

45.20 [18–80]

39.0 [21–71]

40.6 [19–68]

Sex

Males (%)

36 [55.4]

62 [57.9]

13 [72.2]

12 [60]

Females (%)

29 [44.6]

45 [42.1]

5 [27.8]

8 [40]

Smoking

Current (%)

19 [29]

9 [8]

2 [11]

1 [5]

Former (%)

17 [26]

48 [45]

3 [17]

5 [25]

Never (%)

28 [43]

50 [47]

13 [72]

14 [70]

BMI

25 [16–51]

26 [17–56]

24 [19–37]

26 [19–44]

Disease duration

6.7 [0–38]

8.3 [0.1–39]

  

Treatmenta

5-ASA, topical

0 [0]

30 [28]

  

5-ASA, oral

7 [11]

71 [66]

  

Corticosteroids, topical

0 [0]

2 [2]

  

Corticosteroids, oral

4 [6]

7 [6]

  

Corticosteroid, iv

2 [3]

3 [3]

  

Immunosuppressant

23 [35]

18 [17]

  

Biologic agents

39 [60]

22 [21]

  

No treatment

6 [9]

12 [11]

  

Clinical disease activity

HBI (remission/mild/moderate/severe) (n = 65)

41/13/10/1

   

Mayo partial (remission/mild/moderate/severe) (n = 107)

 

52/23/28/4

  

Endoscopic disease activity

SES-CD (remission/mild/moderate/severe) (n = 17)

7/3/5/2

   

Mayo endo (remission/mild/moderate/severe) (n = 63)

 

11/21/20/11

  

Montreal classification CD

Age at diagnosis (A1/A2/A3) (n = 65)

10/46/9

   

Location (L1/L2/L3/L4) (n = 65)

10/24/31/0

   

Behavior (B1/B2/B3) (n = 65)

38/19/8

   

Montreal classification UC

Disease extension (E1/E2/E3) (n = 107)

 

34/47/26

  
  1. HBI: remission (< 5), mild (5–7), moderate (8–16), severe (> 16). Mayo partial: remission (< 2), mild (2–4), moderate (5–7), severe (> 7). SES-CD: Simple endoscopic score of Crohn’s disease: remission (0–2), mild (3–6), moderate (7–15), severe (> 15). Mayo endo: remission (0), mild (1), moderate (2), severe (3). A1: below 16 years, A2: between 17 and 40 years, A3, above 40 years. L1: ileal, L2: colonic, L3: ileocolonic, L4: isolate upper disease. B1: non-stricturing, non-penetrating, B2: stricturing, B3: penetrating. E1: proctitis, E2: Left sided, E3: extensive.
  2. CD Crohn’s disease, UC ulcerative colitis, IBS irritable bowel syndrome, HS healthy subjects.
  3. aSome patients received more than one treatment.