Figure 3 | Scientific Reports

Figure 3

From: Combined detection of peripheral blood VEGF and inflammation biomarkers to evaluate the clinical response and prognostic prediction of non-operative ESCC

Figure 3

4 X-tile analysis of PFS was performed by the X-tile program to determine the optimal cutoff values for VEGF, GPS, CAR, and CLR. The sample of ESCC patients was equally divided into training and validation sets. X-tile plots of training sets are shown in the left panels, with plots of matched validation sets shown in the small inset. The optimal cut-off values highlighted by the black circles in the left panels are shown in histograms of the entire cohort (right panels). p values were determined by using the cutoff values defined in training sets and applying them to validation sets. The optimal cutoff values for VEGF, GPS, CAR, and CLR were 141.3, 0, 0.3, and 6.4, respectively. (a) VEGF, (b) GPS, (c) CAR, and (d) CLR.

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