Figure 7

Invasive ability is promoted by co-culture with live or heat-inactivated F. nucleatum in epithelial phenotype, HOC621 cells. After co-culture with 4 subspecies of live or heat-inactivated F. nucleatum (MOI = 10), invasion ability was determined by in vitro invasion assay in epithelial phenotype, HOC621 cells. (A) Pictures showed the invaded OSCC cells after co-cultured with 4 subspecies of live or heat-inactivated F. nucleatum. (B) Graph shows the number of invaded OSCC cells after co-cultured with 4 subspecies of live or heat-inactivated F. nucleatum. Three independent experiments were used to calculate the mean ± S.D. (*) represents P-value of < 0.05 compared to control (no treatment).