Figure 8 | Scientific Reports

Figure 8

From: Conversion from epithelial to partial-EMT phenotype by Fusobacterium nucleatum infection promotes invasion of oral cancer cells

Figure 8

Remarkable upregulation of p-EMT-related genes by F. nucleatum in epithelial phenotype, HOC621 cells. (A) Heatmap shows the expression levels of epithelial differentiation-related, p-EMT-related, and EMT-related genes after co-culture with heat-inactivated F. nucleatum, P. gingivalis, S. mutans, P. aeruginosa, and E. coli in epithelial phenotype, HOC621 cells. Gene expression data is shown in Supplementary Fig. S8. (B) Schematic model showing that F. nucleatum promotes invasion of OSCC cells via conversion from epithelial to p-EMT phenotype.

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