Table 1 Baseline characteristics of patients stratified by SBP categories.

From: Association of blood pressure and renal outcome in patients with chronic kidney disease; a post hoc analysis of FROM-J study

Characteristics

Overall

n = 2100

Baseline SBP

 < 120

n = 229

120–129

n = 348

130–139

n = 604

140–149

n = 445

150–159

n = 253

160 ≤ 

n = 191

Male sex, %

71.4

72.9

74.3

69.5

69.7

73.5

71.2

Age, year

62.5 ± 8.3

62.4 ± 8.7

61.9 ± 8.8

62.7 ± 8.2

62.3 ± 8.0

62.9 ± 7.7

63.0 ± 8.4

BMI, kg/m2

25.7 ± 3.8

25.4 ± 3.7

25.6 ± 3.8

25.5 ± 3.7

25.8 ± 4.0

26.1 ± 3.7

25.8 ± 4.1

Abdominal girth, cm

90.0 ± 9.9

87.4 ± 10.7

89.0 ± 9.8

90.2 ± 9.7

91.2 ± 9.8

90.6 ± 9.1

91.1 ± 10.4

Current smoking, %

22.5

19.4

24.5

21.7

22.5

24.2

23.0

Diabetes mellitus, %

61.1

58.1

58.5

59.0

61.0

68.4

67.0

Hypertension, %

90.8

77.7

87.5

91.0

95.1

96.1

95.8

Dyslipidemia, %

69.3

66.8

69.5

69.3

71.2

72.3

63.4

Hyperuricemia, %

38.8

39.3

40.3

40.4

35.6

35.2

42.4

Medication

Anti-hypertensive, %

86.1

73,8

81.8

85.9

89.4

93.3

93.2

Use of RAS-I, %

72.8

65.1

70.9

70.5

74.6

79.8

79.6

Laboratory values

Positive proteinuria, %a

80.6

71.6

73.7

80.3

85.4

88.5

85.3

Proteinuria, median (IQR), g/gCr

0.22 (0.06–0.71)

0.16 (0.05–0.39)

0.19 (0.06–0.55)

0.23 (0.06–0.72)

0.26 (0.07–0.87)

0.28 (0.10–0.85)

0.45 (0.08–1.36)

Total protein, g/dL

7.2 ± 0.5

7.2 ± 0.5

7.2 ± 0.5

7.3 ± 0.5

7.3 ± 0.5

7.1 ± 0.5

7.2 ± 0.5

Albumin, g/dL

4.3 ± 0.4

4.2 ± 0.3

4.3 ± 0.3

4.3 ± 0.4

4.3 ± 0.4

4.2 ± 0.4

4.2 ± 0.4

Hemoglobin, g/dL

13.8 ± 1.8

13.6 ± 1.8

13.9 ± 1.8

13.8 ± 1.8

13.9 ± 1.7

13.8 ± 1.9

13.6 ± 2.1

BUN, mg/dL

19.6 ± 8.0

20.2 ± 8.0

18.9 ± 7.2

19.5 ± 8.0

19.4 ± 8.1

19.5 ± 8.4

20.7 ± 8.7

Creatinine, mg/dL

1.07 ± 0.49

1.10 ± 0.44

1.05 ± 0.48

1.07 ± 0.48

1.05 ± 0.49

1.10 ± 0.57

1.16 ± 0.53

eGFR, ml/min/1.73 m2

59.1 ± 21.9

57.0 ± 21.2

60.3 ± 21.1

59.0 ± 22.1

60.8 ± 22.2

59.1 ± 21.7

55.7 ± 22.7

HbA1c, %

6.2 ± 1.2

6.0 ± 1.1

6.1 ± 1.2

6.1 ± 1.1

6.2 ± 1.3

6.3 ± 1.2

6.3 ± 1.1

Uric acid, mg/dL

6.2 ± 1.2

6.2 ± 1.8

6.2 ± 1.5

6.1 ± 1.5

6.1 ± 1.6

6.0 ± 1.5

6.5 ± 1.8

TC, mg/dL

198 ± 35

193 ± 34

195 ± 34

197 ± 37

201 ± 37

195 ± 357

203 ± 33

HDL-C, mg/dL

54 ± 16

55 ± 16

53 ± 15

54 ± 15

56 ± 17

53 ± 14

54 ± 18

Non-HDL-C, mg/dL

147 ± 37

139 ± 34

145 ± 36

147 ± 37

149 ± 39

145 ± 36

153 ± 39

Triglyceride, mg/dL

173 ± 140

151 ± 98

170 ± 131

172 ± 118

176 ± 171

176 ± 136

202 ± 176

  1. Unless otherwise specified, data are presented as the mean ± SD.
  2. SBP systolic blood pressure, BMI body mass index, CKD chronic kidney disease, DBP diastolic blood pressure, RAS-I renin angiotensin system inhibitor, IQR interquartile range, BUN blood urea nitrogen, eGFR estimated glomerular filtration rate, HbA1c hemoglobin A1c, TC total cholesterol, HDL-C high density lipoprotein cholesterol.
  3. aDipstick positive proteinuria of ± or higher.
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