Table 3 Relations of peripheral myeloid-derived suppressor cells and regulatory T cells with blast cells in children with B-cell acute lymphoblastic leukemia.

Cells	PB blast cells	BM blast cells	CD34⁺ cells
Total MDSC	r = 0.1	r = 0.1	r = 0.07
Total MDSC	p = 0.3	p = 0.2	p = 0.4
PMN–MDSCs	r = 0.4	r = 0.4	r = 0.5
PMN–MDSCs	p = 0.007	p = 0.006	p = 0.001
MO-MDSCs	r = − 0.2	r = − 0.2	r = − 0.2
MO-MDSCs	p = 0.1	p = 0.1	p = 0.06
CD4⁺T cells	r = − 0.2	r = − 0.1	r = − 0.3
CD4⁺T cells	p = 0.2	p = 0.2	p = 0.03
CD4⁺CD25^+low	r = 0.2	r = 0.3	r = 0.3
CD4⁺CD25^+low	p = 0.1	p = 0.08	p = 0.03
CD4⁺CD25^+high	r = − 0.2	r = − 0.07	r = − 0.2
CD4⁺CD25^+high	p = 0.2	p = 0.4	p = 0.2
CD4⁺CD25^+highFoxP3⁺ (Tregs)	r = 0.5	r = 0.6	r = 0.5
CD4⁺CD25^+highFoxP3⁺ (Tregs)	p = 0.003	p = 0.001	p = 0.004

PB peripheral blood, BM bone marrow, MDSCs myeloid-derived suppressor cells, PMN—MDSCs: polymorphonuclear myeloid-derived suppressor cells, MO-MDSCs monocytic myeloid-derived suppressor cells, Tregs regulatory T cells. Pearson correlation, r Pearson’s correlation coefficient,
significant p-value < 0.05.

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