Table 2 Characteristics of measurements changes of SSc patients at baseline (Day 0) and 1, 3, 6 and 12-month-follow-up.
Parameter | Day 0 | P* | Month 1 | P* | Month 3 | P* | Month 6 | P* | Month 12 | P* | P† | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SSc | Control | SSc | Control | SSc | Control | SSc | Control | SSc | Control | |||||||||
DASH | 49.4 (11.8) | 52.3 (10.7) | 0.5197 | 33.1 (9.6) | 50.3 (10.4) | 0.0002 | 36.3 (10.4) | 53.1 (10.7) | 0.0006 | 42.6 (11.5) | 53.4 (10.6) | 0.0209 | 48.3 (12.7) | 53.8 (10.9) | 0.2500 | 0.0001 | ||
VAS | 5.3 (1.5) | 5.3 (1.1) | 1.0000 | 2.9 (1.1) | 4.7 (1.1) | 0.0003 | 3.3 (1.2) | 5.0 (1.0) | 0.0006 | 4.1 (1.2) | 5.0 (1.0) | 0.0582 | 5.1 (1.7) | 5.4 (0.9) | 0.3906 | 0.0001 | ||
CHFS | 42.3 (11.0) | 41.2 (12.1) | 0.6756 | 27.9 (7.5) | 38.6 (12.0) | 0.0026 | 30.4 (8.2) | 41.7 (11.9) | 0.0031 | 36.1 (10.2) | 41.5 (11.4) | 0.2189 | 40.6 (10.9) | 42.3 (11.9) | 0.7573 | 0.0001 | ||
HAQ-DI | 1.3 (0.5) | 1.4 (0.6) | 0.6407 | 0.9 (0.5) | 1.4 (0.6) | 0.0323 | 1.1 (0.7) | 1.4 (0.6) | 0.0515 | 1.1 (0.6) | 1.5 (0.6) | 0.1000 | 1.3 (0.6) | 1.5 (0.5) | 0.4499 | 0.0001 | ||
SHAQ | ALL | 1.3 (0.5) | 1.3 (0.5) | 0.6874 | 0.9 (0.4) | 1.3 (0.5) | 0.0394 | 0.9 (0.4) | 1.4 (0.5) | 0.0205 | 1.1 (0.5) | 1.4 (0.6) | 0.1437 | 1.3 (0.5) | 1.4 (0.5) | 0.5827 | 0.0001 | |
RP | 1.6 (0.6) | 1.3 (0.5) | 0.1263 | 1.1 (0.5) | 1.1 (0.5) | 0.6639 | 1.2 (0.5) | 1.3 (0.5) | 0.4991 | 1.4 (0.6) | 1.4 (0.6) | 0.8943 | 1.6 (0.6) | 1.4 (0.5) | 0.2644 | 0.0001 | ||
DU | 1.7 (0.6) | 1.4 (0.5) | 0.1615 | 1.0 (0.5) | 1.3 (0.5) | 0.1924 | 1.2 (0.6) | 1.4 (0.5) | 0.1924 | 1.5 (0.6) | 1.5 (0.4) | 0.8811 | 1.6 (0.6) | 1.5 (0.5) | 0.7835 | 0.0001 | ||
dFTP dom | 5.3 (1.7) | 5.6 (1.1) | 0.4304 | 6.0 (1.7) | 5.8 (1.1) | 0.7233 | 5.9 (1.6) | 5.7 (1.0) | 0.7476 | 5.5 (1.7) | 5.6 (1.0) | 0.8161 | 5.3 (1.8) | 5.6 (1.0) | 0.6065 | 0.0001 | ||
dFTP ndom | 5.3 (1.6) | 5.8 (0.8) | 0.1869 | 6.0 (1.5) | 6.0 (0.8) | 0.7233 | 5.9 (1.6) | 5.9 (0.9) | 0.8469 | 5.6 (1.6) | 5.7 (0.9) | 0.6182 | 5.4 (1.6) | 5.6 (0.8) | 0.3628 | 0.0001 | ||
Kapandi | dom | 5.9 (1.4) | 5.7 (1.0) | 0.6179 | 7.0 (1.7) | 6.7 (1.0) | 0.3675 | 6.7 (1.4) | 6.1 (1.3) | 0.2466 | 6.1 (1.5) | 5.7 (1.2) | 0.4156 | 5.9 (1.6) | 5.4 (1.2) | 0.2949 | 0.0001 | |
ndom | 5.9 (1.1) | 5.5 (1.4) | 0.4689 | 7.0 (1.4) | 5.8 (1.3) | 0.0253 | 6.6 (1.3) | 5.5 (1.2) | 0.0223 | 6.1 (1.2) | 5.3 (1.3) | 0.0628 | 5.8 (1.2) | 5.2 (1.4) | 0.1919 | 0.0001 | ||
Hand grip | dom | 7.7 (2.8) | 8.4 (1.9) | 0.7721 | 8.5 (3.1) | 8.6 (1.9) | 0.7354 | 8.2 (3.0) | 8.3 (1.6) | 0.7476 | 7.7 (2.9) | 8.1 (1.6) | 0.9074 | 7.5 (2.9) | 7.9 (1.6) | 0.9726 | 0.0001 | |
ndom | 8.1 (2.6) | 7.7 (1.7) | 0.7844 | 8.7 (2.8) | 7.7 (1.7) | 0.3590 | 8.5 (2.7) | 7.5 (1.6) | 0.3184 | 8.1 (2.6) | 7.4 (1.6) | 0.4648 | 7.9 (2.5) | 7.2 (1.5) | 0.4499 | 0.0001 | ||
Hand pinch | dom | 3.6 (1.1) | 3.7 (1.1) | 1.0000 | 4.1 (1.1) | 3.7 (1.2) | 0.2738 | 4.0 (1.1) | 3.6 (1.1) | 0.3030 | 3.7 (1.1) | 3.5 (1.1) | 0.3876 | 3.6 (1.1) | 3.4 (1.1) | 0.6092 | 0.0001 | |
ndom | 4.0 (1.0) | 3.4 (1.0) | 0.0974 | 4.5 (1.1) | 3.5 (1.0) | 0.0115 | 4.4 (1.1) | 3.4 (1.0) | 0.0126 | 4.1 (1.0) | 3.3 (1.0) | 0.0191 | 4.0 (1.0) | 3.3 (1.0) | 0.0503 | 0.0001 | ||