Figure 3
From: Role of cholesterol in substrate recognition by \(\gamma\)-secretase
Spatial variations in the average membrane thickness in proximity of the \(\gamma\)-secretase exosite and \(\beta\)-CTF: isolated (left, xy-distance = \(inf\)), at the slope of the free energy profile for the substrate binding (middle, xy-distance = 1.6 nm) and in complex (right, xy-distance = 1.1 nm). The perimeter (p) of the membrane regions thinned by the proteins is represented with dashed lines.
