Figure 5
From: Role of cholesterol in substrate recognition by \(\gamma\)-secretase

2D profiles of the membrane thickness for (a) \(\gamma\)-secretase and (b) \(\beta\)-CTF embedded in pure DPPC membrane. Probability distributions of the membrane thickness in the proximity of initial substrate binding site of \(\gamma\)-secretase (orange), \(\beta\)-CTF (green) or in the bulk (blue) for cholesterol-rich (c) or pure (d) DPPC membrane.