Figure 4 | Scientific Reports

Figure 4

From: Lower peripheral blood Toll-like receptor 3 expression is associated with an unfavorable outcome in severe COVID-19 patients

Figure 4

Quantitative mRNA of Pattern Recognition Receptors (PRRs) in circulating leukocytes of patients with COVID-19 during hospital stay. Expression of PRRs (mRNA) was measured in circulating leukocytes. Blood samples were collected every five days as feasible during hospitalization. The difference between COVID-19 MILD (N = 17 patients) and COVID-19 SEVERE (N = 24 patients) TLR3 and TLR4 mRNA expression at admission widened during follow up. Controls are also shown (17 patients). P values were calculated using the nonparametric Kruskal–Wallis test in R software (version 4.0.3 for macOS).

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