Figure 6

Serum cytokine levels during hospitalization. Circulating cytokines in plasma from the COVID-19 patients was also measured, and the profile was similar to that observed for mRNA. IFN-γ was lower in the SEVERE COVID-19 group (N = 50 patients) when compared to COVID-19 MILD (N = 29 patients), while pro-inflammatory cytokine levels (IL-6, TNF-α, and MCP-1) were higher. P values were calculated using the nonparametric Kruskal–Wallis test in R software (version 4.0.3 for macOS).