Table 1 Antimicrobial activity against S. aureus and C. albicans of dimeric forms of Ctl. MSSA (strain 49775) and MRSA (strain S1); C. albicans, (ATCC 10231TM). ND, not determined.
From: Catestatin in innate immunity and Cateslytin-derived peptides against superbugs
Peptide | Sequence | MIC100 (µM) | ||
|---|---|---|---|---|
MSSA | MRSA | C. albicans | ||
P1 | RSMRLSFRARGYGFR | 50 | 100 | 20 |
P2 | RSMRLSFRARGYGFRC | 60 | 100 | 20 |
P3 | RSMRLSFRARGYGFRC-(3PEG)-CRFGYGRARFSLRMSR | 30 | 50 | 20 |
P4 | RSMRLSFRARGYGFRMal-(12PEG)-MalRFGYGRARFSLRMSR | > 100 | ND | ND |
P5 | RSMRLSFRARGYGFRMal-(16PEG)-MalRFGYGRARFSLRMSR | > 100 | > 100 | 50 |
P6 | RSMRLSFRARGYGFRMal-(46PEG)-MalRFGYGRARFSLRMSR | > 100 | ND | ND |
