Table 1 Patient demographics and characteristics.
AIH (N = 52) | ASC (N = 14) | p value | |
|---|---|---|---|
Patient demographics | |||
Female (%) | 23 (60.5%) | 5 (45.5%) | 0.37 |
Age (years) | 14.4 ± 3.4 | 14.2 ± 3.0 | 0.83 |
BMI (kg/m2) | 20.4 ± 4.1 | 21.4 ± 3.8 | 0.46 |
Time from diagnosis to MRI (years) | 2.2 ± 2.1 | 2.9 ± 3.7 | 0.71 |
Liver biochemistry | |||
Total Bilirubin (mg/dL) | 1.1 ± 1.7 | 0.8 ± 0.4 | 0.47 |
ALT (IU/L) | 181.4 ± 347.9 | 103.8 ± 103.9 | 0.39 |
AST (IU/L) | 168.4 ± 355.7 | 104.4 ± 132.9 | 0.26 |
GGT (IU/L) | 73.3 ± 128.9 | 224.8 ± 399.9 | 0.024 |
IgG (g/L) | 14.0 ± 5.2 | 14.6 ± 4.9 | 0.61 |
Albumin (g/L) | 43.1 ± 5.0 | 42.9 ± 3.0 | 0.47 |
Gamma globulins (%) | 18.9 ± 6.4 | 16.6 ± 4.5 | 0.28 |
Histology scores | |||
Fibrosis | |||
Score 0 | 6 | 2 | |
Score 1 | 10 | 0 | |
Score 2 | 8 | 2 | |
Score 3 | 11 | 4 | |
Score 4 | 7 | 1 | |
Score 5 | 8 | 3 | |
Score 6 | 2 | 2 | |
Portal inflammation | |||
Score 0 | 6 | 1 | |
Score 1 | 17 | 6 | |
Score 2 | 19 | 6 | |
Score 3 | 10 | 1 | |
Lobular inflammation | |||
Score 0 | 17 | 5 | |
Score 1 | 28 | 5 | |
Score 2 | 3 | 3 | |
Score 3 | 4 | 1 | |
