Table 2 Multivariate analysis for associations between serum fatty acid-related metabolites and blood eosinophil counts or neutrophil counts.

From: Impacts of lipid-related metabolites, adiposity, and genetic background on blood eosinophil counts: the Nagahama study

 

Blood eosinophil countsa

Blood neutrophil countsa

β coefficient

95% CI

p value

β coefficient

95% CI

p value

Model 1

BHBa

− 0.074

− 0.096 to − 0.052

< 0.0001

0.162

0.141–0.183

< 0.0001

BMI (kg/m2)

0.067

0.042–0.091

< 0.0001

0.025

0.002–0.048

0.034

BHBa*BMI

0.028

0.007–0.049

0.009

− 0.017

− 0.037 to 0.003

0.099

LAa

− 0.068

− 0.090 to − 0.045

< 0.0001

0.159

0.138–0.180

< 0.0001

BMI (kg/m2)

0.069

0.045–0.093

< 0.0001

0.018

− 0.005 to 0.041

0.12

LAa*BMI

0.028

0.007–0.049

0.009

− 0.032

− 0.052 to − 0.012

0.002

Model 2

BHBa

− 0.077

− 0.099 to − 0.055

< 0.0001

0.161

0.140–0.182

< 0.0001

Body fat percentages (%)

0.079

0.053–0.106

< 0.0001

0.056

0.031–0.082

< 0.0001

BHBa*Body fat

0.028

0.007–0.049

0.010

− 0.008

− 0.028 to 0.012

0.45

LAa

− 0.072

− 0.094 to − 0.049

< 0.0001

0.154

0.132–0.175

< 0.0001

Body fat percentages (%)

0.085

0.058–0.112

< 0.0001

0.046

0.021–0.072

0.0004

LAa*Body fat

0.020

− 0.001 to 0.041

0.066

− 0.024

− 0.044 to − 0.004

0.019

  1. BHB β-hydroxybutyric acid, LA linoleic acid, BMI body mass index, β coefficient standardized partial regression coefficient, CI confidence interval.
  2. aLog-transformed. Multivariate analysis for blood eosinophil counts were adjusted by age, sex, smoking history, elapsed time after a meal, medication for dyslipidemia, serum HDL cholesterol, serum triglycerides, serum total IgE and high-sensitivity CRP. Multivariate analysis for blood neutrophil counts were adjusted by age, sex, smoking history, elapsed time after a meal, medication for dyslipidemia, serum HDL cholesterol, serum triglycerides and high-sensitivity CRP.
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