Table 3 Brain-plasma ratio of LLNL-02 (1) at Tmax following a single IV dose of 14C-LLNL-02 to male guinea pigs.

From: Development of a CNS-permeable reactivator for nerve agent exposure: an iterative, multi-disciplinary approach

LLNL-02 dose (mg/kg)

Brain/plasma

logBB

1

0.132

− 0.879

5

0.224

− 0.650

10

0.488

− 0.311

20

0.529

− 0.276

Back to article page