Figure 1

Comparison of expression profiles of 377 urinary miRNAs in pooled urine samples from recovered and nonrecovered AKI patients. (A,B) Using TaqMan Low Density Array (TLDA) Human microRNA Card A with global normalisation, urinary miRNAs from recovered AKI patients (n = 6), nonrecovered AKI patients (n = 5) and control subjects (n = 20)¹¹ were analysed. Venn diagrams depicting miRNAs with ≥ twofold increased (A) and decreased (B) detection when comparing recovered AKI with controls (dashed circle), non-recovered AKI with controls (dotted circle) and non-recovered AKI with recovered AKI (solid circle). (C) Heatmap showing changes between recovered, non-recovered and controls with a ≥ twofold change in all three comparisons. The heatmap was generated using Morpheus software from the Broad Institute (Morpheus, https://software.broadinstitute.org/morpheus).