Table 2 Variables associated with alcohol consumption and psychiatric comorbidity.

From: Evaluation of neurotrophic factors and education level as predictors of cognitive decline in alcohol use disorder

Variables

Patients with alcohol use disorder

Total sample

N = 262

Subcohort

N = 58

Statisticsa

df

p-value

Age at onset of consumption [mean (SD)] (years)

16.26 (3.9)

15.17 (2.95)

1.670b

314

0.096

Age at the development of dependence [mean (SD)] (years)

29.56 (10.62)

31.23 (11.07)

− 0.946b

347

0.339

Length of AUD diagnosis [mean (SD)] (years)

15.35 (10.41)

16.36 (14.93)

− 0.051b

295

0.964

Severity criteria [mean (range)]

Criteria (0–11)

7.46 (2.19)

7.88 (2.08)

− 1.285b

316

0.200

Duration of abstinence [Mean (mode)] (Days)

306.67 (60)

128.61 (60)

2.443b

312

0.003

Comorbid substance use disorders [N (%)]

Cocaine

77 (29.4)

19 (32.8)

0.326c

1

0.633

Cannabis

34 (13)

6 (10.3)

0.266

 

0.825

Sedatives

18 (6.9)

5 (8.6)

0.245

 

0.579

Comorbid psychiatric disorders N (%)]

Mood

119 (45.4)

25 (43.1)

0.024c

1

1

Anxiety

81 (30.9)

20 (34.5)

0.441

 

0.529

Personality

43 (16.4)

5 (8.6)

2.071

 

0.221

ADHD

54 (20.6)

6 (10.3)

3.028

 

0.217

Psychiatric medication use [N (%)]

Antidepressants

114 (43.5)

31(53.4)

1.821c

1

0.189

Anxiolytics

103 (39.3)

19 (32.8)

0.933

 

0.370

Anticraving

71 (27.1)

19 (32.8)

0.713

 

0.420

Disulfiram use [N (%)]

168 (64.1)

45 (77.6)

0.704c

1

0.590

  1. df degree of freedom.
  2. Bold values are statistically significant for p < 0.05.
  3. aThe statistical analysis was conducted using the logarithmic transformed values to ensure that statistical assumptions were met for age at the onset of consumption, age at the development of dependency, duration AUD, severity criteria met and duration of abstinence.
  4. bStudent’s t test statistic.
  5. cChi-square test statistic.
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