Table 2 Regions of significantly lower GMV in LLD detected in the whole-brain GMV analysis.

From: Lower regional gray matter volume in the absence of higher cortical amyloid burden in late-life depression

Cluster size (voxels)

Brain Regions

Peak MNI coordinates

T values

Cluster-level p

(FWE–corrected)

Voxel-level p

(FWE-corrected)

x

y

z

3295

Left temporal cluster

    

 < 0.001

 

Left middle temporal gyrus

− 64

− 50

6

5.51

 

0.004

 

− 60

− 57

− 4

4.58

 

0.12

Left inferior temporal gyrus

− 50

− 62

− 8

4.81

 

0.055

 

− 38

− 46

− 14

4.14

 

0.40

 

− 51

− 58

− 22

3.96

 

0.57

 

− 50

− 51

− 8

3.77

 

0.77

 

− 46

− 50

− 27

3.39

 

0.98

Left fusiform gyrus

− 22

− 44

− 14

4.61

 

0.11

 

− 34

− 62

− 9

3.99

 

0.54

1399

Left parietal cluster

    

0.005

 

Left middle temporal gyrus

− 51

− 50

22

5.42

 

0.006

Left supramarginal gyrus

− 56

− 46

32

4.53

 

0.14

 

− 58

− 57

28

3.62

 

0.89

1564

Right occipital cluster

      

Right lingual gyrus

14

− 86

− 10

4.37

0.003

0.22

Right middle occipital gyrus

32

− 100

− 2

4.09

 

0.44

Right inferior occipital gyrus

24

− 93

− 6

3.99

 

0.54

 

30

− 86

− 10

3.79

 

0.75

 

44

− 75

− 14

3.77

 

0.77

Right fusiform gyrus

30

− 75

− 16

3.91

 

0.63

 

46

− 58

− 20

3.86

 

0.68

  1. Peak coordinates were local maxima more than 10 mm apart.