Figure 2

Representative 600Ā MHz 1H-NMR spectra of plasma showing the selected eight metabolite signals (Ī“1ā9). x axis, parts per million (ppm); y axis, intensity (a.u.). 1, Acetic acid; 2, Proline; 3, Pyruvic acid; 4, Succinic acid; 5, Glutamine; 6, Glycine; 7, Creatine; 8, Histidine.