Table 2 Cytotoxicity (IC50 ± SEM, μM) of the compounds against A375, HT29 and HFF cell lines for 48 h.

From: Novel Tl(III) complexes containing pyridine-2,6-dicarboxylate derivatives with selective anticancer activity through inducing mitochondria-mediated apoptosis in A375 cells

 

A375

HT29

HFF

C1

81.45 ± 1.02

354.36 ± 0.71

 > 500

C2

421.13 ± 0.55

486.25 ± 0.69

 > 500

C3

7.23 ± 0.93

193.18 ± 1.12

 > 500

pydcH2

442.64 ± 1.22

430.23 ± 2.09

 > 500

hpydcH2

 > 500

 > 500

 > 500

2-ab

 > 500

 > 500

 > 500

4-apy

491.87 ± 1.56

 > 500

 > 500

Oxaliplatin

331.03 ± 2.69

323.13 ± 2.87

429.23 ± 2.32

  1. No significant effect was observed on cells tested for metal salt.
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