Figure 5
From: The zinc finger/RING domain protein Unkempt regulates cognitive flexibility
UnkcKO mice have normal locomotor activity and show a trend towards decreased anxiety. (A) Body weight of control and UnkcKO mice at 12 weeks. (B,C) Sagittal sections of control (B) and UnkcKO (C) mice at P20 stained with haemotoxylin and eosin. (D,E) Open field test measure of distance (D) and velocity (E) of movement in the outer ring of the arena. (F) Open field test, latency to centre. (G,H) Elevated plus (EP) maze test, number of entries to open arms (E), time spent in open arms (H). Control n = 11, UnkcKO n = 8. Data are presented as mean ± SEM. Students t-test, **p < 0.01 compared to control.
